Estrogen DNA Test – Interpretation Guide

Estrogen DNA Test – Interpretation Guide

ESTROGEN DNA TEST

The Estrogen DNA test provides useful genetic information about your body’s ability to optimally make use of estrogen hormones, which can be extremely important for your sexual and overall health.

Estrogen is a type of biological hormone that promotes the development and maintenance of the female physical features and reproductive system. Estrogen also helps promote healthy bones and is involved in essential blood clotting formation. Often times, testosterone and estrogen are mistakenly considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function and is essential for controlling libido and erectile function, as well as the development and production of sperm cells.

Chemical estrogens can be toxic and are also found in the environment in animal hormones, plastic bottles, and certain cosmetics and shampoo. When not metabolized properly, estrogen levels may be higher than they should be, resulting in excess body fat and increased cancer risk. The proper metabolism of estrogen and supporting enzymes is essential for hormone balance, optimal health, and health-risk protection.

Women

Potential side effects of high estrogen levels/poor estrogen metabolism in women include: 

  • Weight Gain

  • Hair Loss

  • Depression

  • Sleep Problems/ Insomnia

  • Ovarian Cysts

  • Endometriosis

  • Fatigue

  • Headaches/Migraines

  • Anxiety

  • Memory Problems

  • Fibrocystic Breast Disease

  • Some Cancers, Including Breast and Ovarian Cancer

 

Men

Potential side effects of high estrogen levels/poor estrogen metabolism in men include:

  • Erectile Dysfunction (ED) Men with high levels of estrogen may have difficulty getting or maintaining an erection.

  • Infertility when estrogen levels are high, sperm levels may fall and cause fertility issues.

  • Gynecomastia Estrogen may stimulate breast growth in men.

Variations in genetic factors contribute to individual differences in estrogen metabolism efficiency. Proteins are functional products of your genetic information, and some proteins, called enzymes, are involved in biochemical reactions and are necessary for effective estrogen metabolism. Some of these enzymes also protect cells from oxidative stress caused by carcinogenic toxins in the environment such as cigarette smoke and certain dietary choices.

Toxin neutralization takes place in the liver, which is an essential organ that supports metabolism, digestion, energy storage, and hormone production. The liver is also the major detoxifying organ in the body, and certain foods and nutrients are known to protect liver tissues from oxidative damage.

The Estrogen test provides an individualized report that will explain how your specific genetic results contribute to the functional outcome of a select panel of enzymes relating to their ability to metabolize estrogen and neutralize toxins so that they can be removed by the body. Your individualized report will discuss ways in which you can help your body to increase this efficiency through dietary supplementation and lifestyle modifications.

The Estrogen DNA test provides an individualized report that will explain how your specific genetic results contribute to the functional outcome of a select panel of enzymes

The Estrogen report will provide customized, healthy lifestyle interventions based on your genetic profile. Key recommendations include select antioxidants, nutrients, and micronutrients that will effectively reduce estrogen load by supporting preferred estrogen pathways and help neutralize toxic substances by optimizing liver detoxification, thus successfully converting these toxins into less harmful ones and ensuring these byproducts can be removed. Additional recommendations will include preferred dietary choices and, when dietary intake is inadequate, ideal high-quality supplements tailored to benefit your metabolic profile.

Ensuring optimal metabolic function is imperative to optimized health and a fundamental understanding of your genetic contribution in modulating a lifetime of exposure to estrogens, estrogen metabolites, and other carcinogens, as provided in the Estrogen Report, will give you the essential tools necessary to facilitate and implement your personalized metabolic health plan.


DNA Basics

DNA

 Deoxyribonucleic acid (DNA) is our hereditary template. Most DNA is located in the cell nucleus within chromosome s, but a small amount is found in the mitochondria (mtDNA).

Bases

The information in DNA is stored as a code made up of four chemical bases:

  • Adenine (A)
  • Guanine (G)
  • Cytosine (C)
  • Thymine (T)

Base pairs

Two DNA base pairs join to make a unit:

  • Adenine (A) pairs with thymine (T)
  • Cytosine (C) pairs with guanine (G)

Nucleotide

One base + one sugar + phosphate = nucleotide

Nucleotides join together and are arranged in two long strands that form a spiral called a double helix.

Replication

Replication takes place when cells divide. It is the process by which DNA copies itself so that the new cell contains the same DNA as the old cell.

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